KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F1
All Species:
16.06
Human Site:
S403
Identified Species:
29.44
UniProt:
Q01094
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01094
NP_005216.1
437
46920
S403
P
E
E
F
I
S
L
S
P
P
H
E
A
L
D
Chimpanzee
Pan troglodytes
XP_524538
437
47536
D408
I
S
F
S
P
S
L
D
Q
D
D
Y
L
W
G
Rhesus Macaque
Macaca mulatta
XP_001103717
502
53768
S468
P
E
E
F
I
S
L
S
P
P
H
E
A
L
D
Dog
Lupus familis
XP_542963
571
61192
S537
P
E
E
F
I
S
L
S
P
P
H
E
A
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61501
430
46305
S396
P
G
E
F
I
S
L
S
P
P
H
E
A
L
D
Rat
Rattus norvegicus
Q62814
300
33206
T274
P
L
L
R
L
S
P
T
P
A
D
D
Y
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
V426
P
Q
T
E
D
Q
L
V
F
G
G
P
M
T
G
Chicken
Gallus gallus
Q90977
403
43534
Y377
S
P
P
Q
P
Q
D
Y
H
F
G
L
E
E
G
Frog
Xenopus laevis
NP_001090608
426
47125
S394
F
I
S
L
S
P
T
S
S
Q
E
Y
S
F
G
Zebra Danio
Brachydanio rerio
NP_001074097
429
46452
L403
S
D
E
Y
M
L
G
L
G
D
E
Q
G
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
A741
P
G
V
A
D
C
D
A
N
S
N
S
S
S
V
Honey Bee
Apis mellifera
XP_396223
416
46049
Y390
L
L
C
E
S
D
D
Y
G
P
M
G
G
G
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
P378
D
D
F
V
A
L
S
P
P
A
V
D
D
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.7
86
70.9
N.A.
84.6
23.1
N.A.
39.9
59.9
49.8
37.2
N.A.
20.6
29.7
N.A.
38.4
Protein Similarity:
100
54.4
86.2
72.6
N.A.
88.5
37.9
N.A.
51.2
70
63.3
53.7
N.A.
31.5
46.4
N.A.
54.2
P-Site Identity:
100
13.3
100
100
N.A.
93.3
20
N.A.
13.3
0
6.6
6.6
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
40
N.A.
20
0
13.3
40
N.A.
26.6
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
8
0
16
0
0
31
0
0
% A
% Cys:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
0
16
8
24
8
0
16
16
16
8
0
31
% D
% Glu:
0
24
39
16
0
0
0
0
0
0
16
31
8
8
0
% E
% Phe:
8
0
16
31
0
0
0
0
8
8
0
0
0
8
8
% F
% Gly:
0
16
0
0
0
0
8
0
16
8
16
8
16
8
31
% G
% His:
0
0
0
0
0
0
0
0
8
0
31
0
0
0
0
% H
% Ile:
8
8
0
0
31
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
8
16
8
8
8
16
47
8
0
0
0
8
8
31
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% N
% Pro:
54
8
8
0
16
8
8
8
47
39
0
8
0
0
0
% P
% Gln:
0
8
0
8
0
16
0
0
8
8
0
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
8
8
8
16
47
8
39
8
8
0
8
16
8
8
% S
% Thr:
0
0
8
0
0
0
8
8
0
0
0
0
0
8
0
% T
% Val:
0
0
8
8
0
0
0
8
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
8
0
0
0
16
0
0
0
16
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _